我们介绍RealityTalk，该系统通过语音驱动的互动虚拟元素来增强实时实时演示。增强演示文稿利用嵌入式视觉效果和动画来吸引和表现力。但是，现有的实时演示工具通常缺乏互动性和即兴创作，同时在视频编辑工具中产生这种效果需要大量的时间和专业知识。RealityTalk使用户能够通过实时语音驱动的交互创建实时增强演示文稿。用户可以通过实时语音和支持方式进行交互提示，移动和操纵图形元素。根据我们对177个现有视频编辑的增强演示文稿的分析，我们提出了一套新颖的互动技术，然后将它们纳入真人秀。我们从主持人的角度评估我们的工具，以证明系统的有效性。

Coronary Computed Tomography Angiography (CCTA) provides information on the presence, extent, and severity of obstructive coronary artery disease. Large-scale clinical studies analyzing CCTA-derived metrics typically require ground-truth validation in the form of high-fidelity 3D intravascular imaging. However, manual rigid alignment of intravascular images to corresponding CCTA images is both time consuming and user-dependent. Moreover, intravascular modalities suffer from several non-rigid motion-induced distortions arising from distortions in the imaging catheter path. To address these issues, we here present a semi-automatic segmentation-based framework for both rigid and non-rigid matching of intravascular images to CCTA images. We formulate the problem in terms of finding the optimal \emph{virtual catheter path} that samples the CCTA data to recapitulate the coronary artery morphology found in the intravascular image. We validate our co-registration framework on a cohort of $n=40$ patients using bifurcation landmarks as ground truth for longitudinal and rotational registration. Our results indicate that our non-rigid registration significantly outperforms other co-registration approaches for luminal bifurcation alignment in both longitudinal (mean mismatch: 3.3 frames) and rotational directions (mean mismatch: 28.6 degrees). By providing a differentiable framework for automatic multi-modal intravascular data fusion, our developed co-registration modules significantly reduces the manual effort required to conduct large-scale multi-modal clinical studies while also providing a solid foundation for the development of machine learning-based co-registration approaches.

Artificial intelligence(AI) systems based on deep neural networks (DNNs) and machine learning (ML) algorithms are increasingly used to solve critical problems in bioinformatics, biomedical informatics, and precision medicine. However, complex DNN or ML models that are unavoidably opaque and perceived as black-box methods, may not be able to explain why and how they make certain decisions. Such black-box models are difficult to comprehend not only for targeted users and decision-makers but also for AI developers. Besides, in sensitive areas like healthcare, explainability and accountability are not only desirable properties of AI but also legal requirements -- especially when AI may have significant impacts on human lives. Explainable artificial intelligence (XAI) is an emerging field that aims to mitigate the opaqueness of black-box models and make it possible to interpret how AI systems make their decisions with transparency. An interpretable ML model can explain how it makes predictions and which factors affect the model's outcomes. The majority of state-of-the-art interpretable ML methods have been developed in a domain-agnostic way and originate from computer vision, automated reasoning, or even statistics. Many of these methods cannot be directly applied to bioinformatics problems, without prior customization, extension, and domain adoption. In this paper, we discuss the importance of explainability with a focus on bioinformatics. We analyse and comprehensively overview of model-specific and model-agnostic interpretable ML methods and tools. Via several case studies covering bioimaging, cancer genomics, and biomedical text mining, we show how bioinformatics research could benefit from XAI methods and how they could help improve decision fairness.

Automatic medical image classification is a very important field where the use of AI has the potential to have a real social impact. However, there are still many challenges that act as obstacles to making practically effective solutions. One of those is the fact that most of the medical imaging datasets have a class imbalance problem. This leads to the fact that existing AI techniques, particularly neural network-based deep-learning methodologies, often perform poorly in such scenarios. Thus this makes this area an interesting and active research focus for researchers. In this study, we propose a novel loss function to train neural network models to mitigate this critical issue in this important field. Through rigorous experiments on three independently collected datasets of three different medical imaging domains, we empirically show that our proposed loss function consistently performs well with an improvement between 2%-10% macro f1 when compared to the baseline models. We hope that our work will precipitate new research toward a more generalized approach to medical image classification.

Migraine is a high-prevalence and disabling neurological disorder. However, information migraine management in real-world settings could be limited to traditional health information sources. In this paper, we (i) verify that there is substantial migraine-related chatter available on social media (Twitter and Reddit), self-reported by migraine sufferers; (ii) develop a platform-independent text classification system for automatically detecting self-reported migraine-related posts, and (iii) conduct analyses of the self-reported posts to assess the utility of social media for studying this problem. We manually annotated 5750 Twitter posts and 302 Reddit posts. Our system achieved an F1 score of 0.90 on Twitter and 0.93 on Reddit. Analysis of information posted by our 'migraine cohort' revealed the presence of a plethora of relevant information about migraine therapies and patient sentiments associated with them. Our study forms the foundation for conducting an in-depth analysis of migraine-related information using social media data.

Physics-Informed Neural Networks (PINNs) are gaining popularity as a method for solving differential equations. While being more feasible in some contexts than the classical numerical techniques, PINNs still lack credibility. A remedy for that can be found in Uncertainty Quantification (UQ) which is just beginning to emerge in the context of PINNs. Assessing how well the trained PINN complies with imposed differential equation is the key to tackling uncertainty, yet there is lack of comprehensive methodology for this task. We propose a framework for UQ in Bayesian PINNs (B-PINNs) that incorporates the discrepancy between the B-PINN solution and the unknown true solution. We exploit recent results on error bounds for PINNs on linear dynamical systems and demonstrate the predictive uncertainty on a class of linear ODEs.

Time-critical control applications typically pose stringent connectivity requirements for communication networks. The imperfections associated with the wireless medium such as packet losses, synchronization errors, and varying delays have a detrimental effect on performance of real-time control, often with safety implications. This paper introduces multi-service edge-intelligence as a new paradigm for realizing time-critical control over wireless. It presents the concept of multi-service edge-intelligence which revolves around tight integration of wireless access, edge-computing and machine learning techniques, in order to provide stability guarantees under wireless imperfections. The paper articulates some of the key system design aspects of multi-service edge-intelligence. It also presents a temporal-adaptive prediction technique to cope with dynamically changing wireless environments. It provides performance results in a robotic teleoperation scenario. Finally, it discusses some open research and design challenges for multi-service edge-intelligence.

One of the weaknesses of classical (fuzzy) rough sets is their sensitivity to noise, which is particularly undesirable for machine learning applications. One approach to solve this issue is by making use of fuzzy quantifiers, as done by the vaguely quantified fuzzy rough set (VQFRS) model. While this idea is intuitive, the VQFRS model suffers from both theoretical flaws as well as from suboptimal performance in applications. In this paper, we improve on VQFRS by introducing fuzzy quantifier-based fuzzy rough sets (FQFRS), an intuitive generalization of fuzzy rough sets that makes use of general unary and binary quantification models. We show how several existing models fit in this generalization as well as how it inspires novel ones. Several binary quantification models are proposed to be used with FQFRS. We conduct a theoretical study of their properties, and investigate their potential by applying them to classification problems. In particular, we highlight Yager's Weighted Implication-based (YWI) binary quantification model, which induces a fuzzy rough set model that is both a significant improvement on VQFRS, as well as a worthy competitor to the popular ordered weighted averaging based fuzzy rough set (OWAFRS) model.

The increase in the number of unmanned aerial vehicles a.k.a. drones pose several threats to public privacy, critical infrastructure and cyber security. Hence, detecting unauthorized drones is a significant problem which received attention in the last few years. In this paper, we present our experimental work on three drone detection methods (i.e., acoustic detection, radio frequency (RF) detection, and visual detection) to evaluate their efficacy in both indoor and outdoor environments. Owing to the limitations of these schemes, we present a novel encryption-based drone detection scheme that uses a two-stage verification of the drone's received signal strength indicator (RSSI) and the encryption key generated from the drone's position coordinates to reliably detect an unauthorized drone in the presence of authorized drones.

This book provides a solution to the control and motion planning design for an octocopter system. It includes a particular choice of control and motion planning algorithms which is based on the authors' previous research work, so it can be used as a reference design guidance for students, researchers as well as autonomous vehicles hobbyists. The control is constructed based on a fault tolerant approach aiming to increase the chances of the system to detect and isolate a potential failure in order to produce feasible control signals to the remaining active motors. The used motion planning algorithm is risk-aware by means that it takes into account the constraints related to the fault-dependant and mission-related maneuverability analysis of the octocopter system during the planning stage. Such a planner generates only those reference trajectories along which the octocopter system would be safe and capable of good tracking in case of a single motor fault and of majority of double motor fault scenarios. The control and motion planning algorithms presented in the book aim to increase the overall reliability of the system for completing the mission.